Article
HLA class II associations with Type 1 diabetes mellitus: a multivariate approach.
Tissue antigens - 1 Feb 2001
Schipper R F, Koeleman B P, Bruining G J, Schreuder G M, Verduijn W, De Vries R R, Roep B O
Abstract excerpt
The association of HLA class II phenotype with the development of insulin-dependent (Type 1) diabetes mellitus (IDDM) is well established but the contribution of the various HLA-DR and -DQ alleles and haplotypes to disease predisposition is not fully understood. We have determined haplotype and genotype odds ratios, and further employed multivariate tree analysis to explore the contribution of individual HLA-DRDQ...
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