Article
Calmodulin and profilin coregulate axon outgrowth in Drosophila.
Journal of neurobiology - 1 Apr 2001
Kim Y S, Furman S, Sink H, VanBerkum M F
Abstract excerpt
Coordinated regulation of actin cytoskeletal dynamics is critical to growth cone movement. The intracellular molecules calmodulin and profilin actively regulate actin-based motility and participate in the signaling pathways used to steer growth cones. Here we show that in the developing Drosophila embryo, calmodulin and profilin convey complimentary information that is necessary for appropriate growth cone...
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