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Article

Polymorphisms in the microsomal epoxide hydrolase gene: role in lung cancer susceptibility and prognosis.

Tumori - 1 Jan 2000

Erkisi Zelal, Yaylim-Eraltan Ilhan, Turna Akif, Görmüs Uzay, Camlica Hakan, Isbir Turgay

Abstract excerpt

AIMS AND BACKGROUND: The aim of this study was to investigate the relationship between EPHXI exon 3 Tyr113His and exon 4 His139Arg polymorphisms, predicted microsomal epoxide hydrolase (mEH) activity, and lung cancer development. mEH is a protective enzyme involved in oxidative defences against a number of environmental chemicals and pollutants, but it is also responsible for the xenobiotic activation of...

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Source

Identifiers

PMID: 21302624
DOI: 10.1177/030089161009600519

Genes

EPHX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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