Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis.

Microbiology (Reading, England) - 1 Jul 1999

Sudoh Masayuki, Tatsuno Kenji, Ono Naomi, Ohta Atsunori, Chibana Hiroji, Yamada-Okabe Hisafumi, Arisawa Mikio

Abstract excerpt

The Candida albicans CHS4 gene encoding chitin synthase 4 has been isolated using the Saccharomyces cerevisiae CHS4/SKT5 gene as a probe. The gene contains a 2061 bp open reading frame capable of encoding a protein of 687 amino acids (76053 Da). No intron was observed in the gene. Disruption of CHS4 in C. albicans yielded a Calcofluor-resistant phenotype, indicating that Chs4p contributes to chitin biosynthesis....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Benzenesulfonates
Share to Blotting, Southern

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Candida albicans

Share to Cell Wall

Share to Chitin

Share to Chitin Synthase

Share to Genes, Fungal

Share to Staining and Labeling

Source

Identifiers

PMID: 10439400
DOI: 10.1099/13500872-145-7-1613

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Candida albicans CHS4 gene complements a Saccharomyces cerevisiae skt5/chs4 mutation and is involved in chitin biosynthesis.PMID 10439400Read ↗

Characterization of CHS4 (CAL2), a gene of Saccharomyces cerevisiae involved in chitin biosynthesis and allelic to SKT5 and CSD4.Semantic proximity Read ↗

Candida albicans strains deficient in CHS7, a key regulator of chitin synthase III, exhibit morphogenetic alterations and attenuated virulence.Semantic proximity Read ↗

Loss of CHT3 in Candida albicans wild-type strains increases surface-exposed chitin and affects host-pathogen interactionSemantic proximity Read ↗

Aspergillus fumigatus chsE: a gene related to CHS3 of Saccharomyces cerevisiae and important for hyphal growth and conidiophore development but not pathogenicity.Semantic proximity Read ↗

An Ashbya gossypii cts2 mutant deficient in a sporulation-specific chitinase can be complemented by Candida albicans CHT4.Semantic proximity Read ↗

KNR4, a suppressor of Saccharomyces cerevisiae cwh mutants, is involved in the transcriptional control of chitin synthase genes.Semantic proximity Read ↗

An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae.Semantic proximity Read ↗

Expression of Paracoccidioides brasiliensis CHS3 in a Saccharomyces cerevisiae chs3 null mutant demonstrates its functionality as a chitin synthase gene.Semantic proximity Read ↗

Chitin synthase III: synthetic lethal mutants and "stress related" chitin synthesis that bypasses the CSD3/CHS6 localization pathway.Semantic proximity Read ↗

Attenuated virulence of chitin-deficient mutants of Candida albicans.Semantic proximity Read ↗

Molecular cloning and characterization of chitinase genes from Candida albicans.Semantic proximity Read ↗

Chs1 of Candida albicans is an essential chitin synthase required for synthesis of the septum and for cell integrity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.