Article
Cell wall protection by the Candida albicans class I chitin synthases.
Fungal genetics and biology : FG & B - 1 Sept 2015
Preechasuth Kanya, Anderson Jeffrey C, Peck Scott C, Brown Alistair J P, Gow Neil A R, Lenardon Megan D
Abstract excerpt
Candida albicans has four chitin synthases from three different enzyme classes which deposit chitin in the cell wall, including at the polarized tips of growing buds and hyphae, and sites of septation. The two class I enzymes, Chs2 and Chs8, are responsible for most of the measurable chitin synthase activity in vitro, but their precise biological functions in vivo remain obscure. In this work, detailed phenotypic...
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