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Article

Physical interaction between p53 and primary response gene Egr-1.

International journal of oncology - 1 Apr 2001

Liu J, Grogan L, Nau M M, Allegra C J, Chu E, Wright J J

Abstract excerpt

The tumor suppressor p53 and primary response gene Egr-1 are nuclear transcription factors with regulatory roles in signal transduction pathways mediating cellular proliferation and growth arrest as well as the complex genetic programs controlling differentiation and programmed cell death. We identified a physical association between these regulatory proteins in vitro and in vivo. Recombinant p53 and Egr-1 fusion...

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Source

Identifiers

PMID: 11251186
DOI: 10.3892/ijo.18.4.863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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