Article
[The molecular interaction between P53 and telomeric repeat binding protein 1 in vitro].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 1 Oct 2004
Li Ling, Zhang Bo, Zou Wan-zhong, Zheng Jie
Abstract excerpt
OBJECTIVE: Cellular proliferate inhibition, senescence or apoptosis are induced by telomere shortening through the activation of P53 pathway, but so far, little is known of the mechanism. This study aimed to clarify the molecular regulation of P53 through telomere pathway by the investigation of molecular interaction between P53 and the main telomere associated protein telomeric repeat binding protein 1(TRBP1) in...
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