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Article

A single histone H1 isoform (H1.1) is essential for chromatin silencing and germline development in Caenorhabditis elegans.

Development (Cambridge, England) - 1 Apr 2001

Jedrusik M A, Schulze E

Abstract excerpt

In remarkable contrast to somatic cells, the germline of the nematode Caenorhabditis elegans efficiently silences transgenic DNA. The molecular mechanisms responsible for this have been shown to implicate chromatin proteins encoded by the mes genes (Kelly, W. G. and Fire, A. (1998) Development 125, 2451-2456), of which two are the C. elegans homologs of Polycomb Group gene transcriptional repressors. We have...

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PMID: 11245572
DOI: 10.1242/dev.128.7.1069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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