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Article

Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.

Molecular and cellular biology - 1 Mar 2001

de Hoog C L, Koehler J A, Goldstein M D, Taylor P, Figeys D, Moran M F

Abstract excerpt

Ras is a small GTPase that is activated by upstream guanine nucleotide exchange factors, one of which is Ras-GRF2. GRF2 is a widely expressed protein with several recognizable sequence motifs, including a Ras exchanger motif (REM), a PEST region containing a destruction box (DB), and a Cdc25 doma...

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Identifiers

PMID: 11238945
DOI: 10.1128/MCB.21.6.2107-2117.2001
PMCID: PMC86827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11238945-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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