Article
SmgGDS displays differential binding and exchange activity towards different Ras isoforms.
Oncogene - 4 Apr 2002
Vikis Haris G, Stewart Scott, Guan Kun-Liang
Abstract excerpt
Ras family GTPases play central roles in a wide variety of biological responses, including cell proliferation, differentiation, and oncogenic transformation. We searched for novel guanine nucleotide exchange factors of HRas and isolated small G-protein dissociation stimulator (smgGDS), a guanine...
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