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Article

G Protein Mono-ubiquitination by the Rsp5 Ubiquitin Ligase.

The Journal of biological chemistry - 27 Mar 2009

Torres Matthew P, Lee Michael J, Ding Feng, Purbeck Carrie, Kuhlman Brian, Dokholyan Nikolay V, Dohlman Henrik G

Abstract excerpt

Emerging evidence suggests that ubiquitination serves as a protein trafficking signal in addition to its well characterized role in promoting protein degradation. The yeast G protein alpha subunit Gpa1 represents a rare example of a protein that undergoes both mono- and poly-ubiquitination. Whereas mono-ubiquitinated Gpa1 is targeted to the vacuole, poly-ubiquitinated Gpa1 is directed instead to the proteasome....

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Share to Endosomal Sorting Complexes Required for Transport
Share to GTP-Binding Protein alpha Subunits, Gq-G11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proteasome Endopeptidase Complex

Share to Protein Processing, Post-Translational

Share to Saccharomyces cerevisiae Proteins

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Source

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Identifiers

PMID: 19176477
DOI: 10.1074/jbc.M809058200
PMCID: PMC2659251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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