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Article

Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver.

Molecular and cellular biology - 1 Mar 2001

Alonzi T, Maritano D, Gorgoni B, Rizzuto G, Libert C, Poli V

Abstract excerpt

We generated mice carrying a STAT3 allele amenable to Cre-mediated deletion and intercrossed them with Mx-Cre transgenic mice, in which the expression of Cre recombinase can be induced by type I interferon. Interferon-induced deletion of STAT3 occurred very efficiently (more than 90%) in the live...

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Source

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Identifiers

PMID: 11238899
DOI: 10.1128/MCB.21.5.1621-1632.2001
PMCID: PMC86708

Genes

STAT3
EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11238899-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Essential role of STAT3 in the control of the acute-phase response as revealed by inducible gene inactivation [correction of activation] in the liver.PMID 11238899Read ↗

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