Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells

Abstract excerpt

BACKGROUND: The signal transducer and activator of transcription 3 (STAT3) mediates gene expression in response to numerous growth factors and cytokines, playing an important role in many cellular processes. To better understand the molecular mechanisms by which Stat3 influences gene expression in the lung, the effect of pulmonary epithelial cell specific deletion of Stat3 on genome wide mRNA expression profiling...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cytokine Signaling Pathways and Interactions
• Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Share to Neonatal Respiratory Health Research