Article
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress.
The EMBO journal - 1 Mar 2001
Proft M, Pascual-Ahuir A, de Nadal E, Ariño J, Serrano R, Posas F
Abstract excerpt
Exposure of yeast to increases in extracellular osmolarity activates the Hog1 mitogen-activated protein kinase (MAPK), which is essential for the induction of gene expression required for cell survival upon osmotic stress. Several genes are regulated in response to osmotic stress by Sko1, a trans...
Topics
- Amino Acid Sequence
- Basic-Leucine Zipper Transcription Factors
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Reporter
- Immunoblotting
- Mitogen-Activated Protein Kinases
- Molecular Sequence Data
- Mutation
- Nuclear Proteins
- Osmotic Pressure
- Phosphorylation