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Article

The Hog1 mitogen-activated protein kinase mediates a hypoxic response in Saccharomyces cerevisiae.

Genetics - 1 Jun 2011

Hickman Mark J, Spatt Dan, Winston Fred

Abstract excerpt

We have studied hypoxic induction of transcription by studying the seripauperin (PAU) genes of Saccharomyces cerevisiae. Previous studies showed that PAU induction requires the depletion of heme and is dependent upon the transcription factor Upc2. We have now identified additional factors required for PAU induction during hypoxia, including Hog1, a mitogen-activated protein kinase (MAPK) whose signaling pathway...

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Identifiers

PMID: 21467572
DOI: 10.1534/genetics.111.128322
PMCID: PMC3122313

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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