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Article

Plc1p is required for SAGA recruitment and derepression of Sko1p-regulated genes.

Molecular biology of the cell - 1 Jul 2007

Guha Nilanjan, Desai Parima, Vancura Ales

Abstract excerpt

In Saccharomyces cerevisiae, many osmotically inducible genes are regulated by the Sko1p-Ssn6p-Tup1p complex. On osmotic shock, the MAP kinase Hog1p associates with this complex, phosphorylates Sko1p, and converts it into an activator that subsequently recruits Swi/Snf and SAGA complexes. We have found that phospholipase C (Plc1p encoded by PLC1) is required for derepression of Sko1p-Ssn6p-Tup1p-controlled...

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Identifiers

PMID: 17429070
DOI: 10.1091/mbc.e06-10-0946
PMCID: PMC1924823

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Plc1p is required for SAGA recruitment and derepression of Sko1p-regulated genes.PMID 17429070Read ↗

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