Article
Rheumatoid arthritis in southern Spain: toward elucidation of a unifying role of the HLA class II region in disease predisposition.
Arthritis and rheumatism - 1 Feb 2001
Pascual M, Nieto A, López-Nevot M A, Ramal L, Matarán L, Caballero A, Alonso A, Martín J, Zanelli E
Abstract excerpt
OBJECTIVE: To evaluate the contributions of HLA-DQ and -DR polymorphisms to susceptibility to rheumatoid arthritis (RA) in a population in southern Spain, and to compare the value of the shared epitope (SE) and RA protection (RAP) models in accounting for the HLA class II region's contribution to RA predisposition. METHODS: One hundred sixty RA patients and 153 healthy controls were typed for HLA-DRB1 and -DQB1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.