Influence of HLA-DR alleles on rheumatoid arthritis: susceptibility and severity in Argentine patients.

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Article

Influence of HLA-DR alleles on rheumatoid arthritis: susceptibility and severity in Argentine patients.

The Journal of rheumatology - 1 Jul 2001

Citera G, Padulo L A, Fernandez G, Lazaro M A, Rosemffet M G, Maldonado Cocco J A

Abstract excerpt

OBJECTIVE: To determine the frequency of shared epitopes in our population of patients with rheumatoid arthritis (RA) and to investigate whether the presence of these alleles is associated with a more aggressive form of disease. METHODS: Demographic and clinical data were obtained from 140 patients with RA, 123 female, mean age 49.9+/-11.7 years and mean disease duration 9.4+/-6.3 years. Radiographs of both hands...

Topics

Adult
Aged
Alleles
Argentina
Arthritis, Rheumatoid
Epitopes
Female
Genetic Predisposition to Disease
Genotype
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DR3 Antigen
Humans
Male
Middle Aged
Severity of Illness Index

Source

Open in PubMed

Identifiers

PMID: 11469451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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