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Article

An extended HLA-DQ-DR haplotype rather than DRB1 alone contributes to RA predisposition.

Immunogenetics - 1 Jan 2000

Zanelli E, Huizinga T W, Guerne P A, Vischer T L, Tiercy J M, Verduyn W, Schreuder G M, Breedveld F C, de Vries R R

Abstract excerpt

In the present study, we tested our hypothesis on the role of a DQ-DR haplotype in rheumatoid arthritis (RA) predisposition. Using two groups of patients and controls, one from The Netherlands and one from Switzerland, we found that DQA1*0301-homozygous and DQA1*0301//DQA1*0101/04-heterozygous individuals are highly predisposed to RA in both populations, while DQA1*0101/04-homozygous are not. The...

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Identifiers

PMID: 9799335
DOI: 10.1007/s002510050450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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