Article
[Clinical and genetic heterogeneity of rheumatoid arthritis].
Postepy higieny i medycyny doswiadczalnej - 1 Jan 2000
Klimiuk P A, Weyand C M, Sierakowski S, Goronzy J J
Abstract excerpt
The diagnostic category of rheumatoid arthritis, a syndrome of chronic inflammatory disease of the synovial membrane and of extraarticular tissues, covers a broad spectrum of clinical phenotypes. Here we propose that distinct combinations of disease risk genes produce heterogeneity of rheumatoid disease. Recognition of this genetic and clinical heterogeneity has immediate implications as it provides the...
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