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Article

Effect of hydrophobicity and molecular mass on the accumulation of fluoroquinolones by Staphylococcus aureus.

The Journal of antimicrobial chemotherapy - 1 Mar 2001

Piddock L J, Jin Y F, Griggs D J

Abstract excerpt

Ten novel fluoroquinolones, with similar chemical structures but differing antibacterial activities and hydrophobicities, were studied to evaluate the role of the physical properties of quinolones on their accumulation and antibacterial activity for Staphylococcus aureus. Six of the 10 agents and tosufloxacin were more active against quinolone-susceptible and -resistant S. aureus than the remaining four agents...

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Source

Identifiers

PMID: 11222558
DOI: 10.1093/jac/47.3.261

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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