In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.

doi:10.1093/jac/49.3.455

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Article

In vitro and in vivo antibacterial activity of T-3912, a novel non-fluorinated topical quinolone.

The Journal of antimicrobial chemotherapy - 1 Mar 2002

Yamakawa Tetsumi, Mitsuyama Junichi, Hayashi Kazuya

Abstract excerpt

The in vitro and in vivo activity of T-3912, a novel non-fluorinated topical quinolone, was compared with that of nadifloxacin, ofloxacin, levofloxacin, clindamycin, erythromycin and gentamicin. The in vitro activity of T-3912 against methicillin-susceptible Staphylococcus aureus, ofloxacin-resistant and methicillin-resistant S. aureus, Staphylococcus epidermidis, ofloxacin-resistant S. epidermidis,...

Topics

Animals
Anti-Infective Agents
Clindamycin
Colony Count, Microbial
DNA Topoisomerase IV
Drug Resistance, Bacterial
Erythromycin
Fluoroquinolones
Gene Frequency
Genes, Bacterial
Gentamicins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Levofloxacin

Male

Mice

Mice, Inbred ICR

Microbial Sensitivity Tests

Mutation

Ofloxacin

Source

Open in PubMed

Identifiers

PMID: 11864945
DOI: 10.1093/jac/49.3.455

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