Article
The role of Serratia marcescens porins in antibiotic resistance.
Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2003
Ruiz Neus, Montero Teresa, Hernandez-Borrell Jordi, Viñas Miquel
Abstract excerpt
The outer membrane permeability of Serratia marcescens was studied by comparing porin-deficient mutants with their parental strains. Omp1-deficient strains were selected by moxalactam resistance, whereas mutants lacking the Omp2 porin were obtained by experimental infection with the SMP2 phage, whose primary receptor is the Omp2 porin. The role of porins was demonstrated in quinolone accumulation assays, where...
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