Article
Activity of gatifloxacin in an in vitro pharmacokinetic-pharmacodynamic model against Staphylococcus aureus strains either susceptible to ciprofloxacin or exhibiting various levels and mechanisms of ciprofloxacin resistance.
Antimicrobial agents and chemotherapy - 1 Jun 2006
Ba Boubakar B, Arpin Corinne, Vidaillac Céline, Chausse Arnaud, Saux Marie-Claude, Quentin Claudine
Abstract excerpt
Gatifloxacin (GAT) is a new 8-methoxy fluoroquinolone with enhanced activity against gram-positive cocci. Its activity was studied in an in vitro pharmacokinetic-pharmacodynamic model against five Staphylococcus aureus strains, either susceptible to ciprofloxacin or exhibiting various levels and mechanisms of ciprofloxacin (CIP) resistance: the ATCC 25923 reference strain (MICs of CIP and GAT: 0.5 and 0.1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.