Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential interactions between GSTM1 and NAT2 genotypes on aromatic DNA adduct level and HPRT mutant frequency in lung cancer patients and population controls.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2001

Hou S M, Fält S, Yang K, Nyberg F, Pershagen G, Hemminki K, Lambert B

Abstract excerpt

We have studied the influence of GSTM1 and NAT2 genotypes on aromatic DNA adduct level (AL) and HPRT mutant frequency (MF) in smokers with newly diagnosed lung cancer and matched population controls. AL was analyzed in relation to genotypes in 170 cases and 144 controls (113 current/recent smokers and 201 former/never smokers), and MF in 157 cases and 152 controls (155 ever smokers and 154 never smokers). Both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Confidence Intervals

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Adducts

Share to Glutathione Transferase

Share to Hypoxanthine Phosphoribosyltransferase

Share to Probability

Share to Reference Values

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 11219770

Genes

NAT2
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential interactions between GSTM1 and NAT2 genotypes on aromatic DNA adduct level and HPRT mutant frequency in lung cancer patients and population controls.PMID 11219770Read ↗

Synergistic effects of NAT2 slow and GSTM1 null genotypes on carcinogen DNA damage in the lung.Semantic proximity Read ↗

Sequence variants of NAT1 and NAT2 and other xenometabolic genes and risk of lung and aerodigestive tract cancers in Central Europe.Semantic proximity Read ↗

Hprt mutant frequency and aromatic DNA adduct level in non-smoking and smoking lung cancer patients and population controls.Semantic proximity Read ↗

Glutathione S-transferase mu1 and N-acetyltransferase 2 genetic polymorphisms and exposure to tobacco smoke in nonsmoking and smoking lung cancer patients and population controls.Semantic proximity Read ↗

Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers.Semantic proximity Read ↗

NAT2 slow acetylation and GSTM1 null genotypes may increase postmenopausal breast cancer risk in long-term smoking women.Semantic proximity Read ↗

N-acetyltransferase NAT1 and NAT2 genotypes and lung cancer risk.Semantic proximity Read ↗

Association of arylamine N-acetyltransferases NAT1 and NAT2 genotypes to laryngeal cancer risk.Semantic proximity Read ↗

NAT2 and CYP1A2 polymorphisms and lung cancer risk in relation to smoking status.Semantic proximity Read ↗

NAT1 and NAT2 genetic polymorphisms and environmental exposure as risk factors for oesophageal squamous cell carcinoma: a case-control study.Semantic proximity Read ↗

GSTM1 null and NAT2 slow acetylation genotypes, smoking intensity and bladder cancer risk: results from the New England bladder cancer study and NAT2 meta-analysis.Semantic proximity Read ↗

Evidence for an intensity-dependent interaction of NAT2 acetylation genotype and cigarette smoking in the Spanish Bladder Cancer Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.