Article
NAT2 and CYP1A2 polymorphisms and lung cancer risk in relation to smoking status.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2000
Osawa Yasunori, Osawa Kayo Kumar, Miyaishi Aiko, Higuchi Miho, Tsutou Akimitsu, Matsumura Sueo, Tabuchi Yoshiki, Tsubota Noriaki, Takahashi Juro
Abstract excerpt
We investigated the associations between lung cancer and the gene polymorphisms of the drug metabolizing enzymes, containing cytochrome P450 1A1 (CYP1A1), cytochrome P450 1A2 (CYP1A2), glutathione S-transferase class mu (GSTM1), and N-acetyltransferase 2 (NAT2). The study involved 113 lung cancer patients and 121 non-cancer controls divided into never, light and heavy smokers according to pack-years of smoking in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
