Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers.

doi:10.1093/carcin/16.8.1913

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Article

Relationship between hprt mutant frequency, aromatic DNA adducts and genotypes for GSTM1 and NAT2 in bus maintenance workers.

Carcinogenesis - 1 Aug 1995

Hou S M, Lambert B, Hemminki K

Abstract excerpt

We have studied the mutant frequency in the human gene for hypoxanthine-guanine phosphoribosyl transferase (hprt) using the T-cell cloning assay, the aromatic DNA adduct level using the 32P-postlabelling assay, and related the levels of these biomarkers to the genotypes for glutathione transferas...

Topics

Adult
Arylamine N-Acetyltransferase
Base Sequence
DNA Adducts
Genotype
Glutathione Transferase
Humans
Hypoxanthine Phosphoribosyltransferase
Isoenzymes
Male
Molecular Sequence Data
Mutation
Occupational Exposure
Vehicle Emissions

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