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Article

Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes.

Cellular microbiology - 1 Jul 1999

Scianimanico S, Desrosiers M, Dermine J F, Méresse S, Descoteaux A, Desjardins M

Abstract excerpt

We have shown recently that one of the survival strategies used by Leishmania donovani promastigotes during the establishment of infection in macrophages consists in inhibiting phagosome-endosome fusion. This inhibition requires the expression of lipophosphoglycan (LPG), the predominant surface glycoconjugate of promastigotes, as parasites expressing truncated forms of LPG reside in phagosomes that fuse...

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Source

Identifiers

PMID: 11207538
DOI: 10.1046/j.1462-5822.1999.00002.x

Genes

LAMP1
EEA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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