Article

A lysophospholipase plays role in generation of neutral-lipids required for hemozoin formation in malaria parasite

2019-10-20

Abstract excerpt

Phospholipid metabolism is crucial for membrane dynamics in malaria parasites during entire cycle in the host cell. Plasmodium falciparum harbours several members of phospholipase family, which play key role in phospholipid metabolism. Here we have functionally characterized a parasite lysophospholipase ( Pf LPL1) with a view to understand its role in lipid homeostasis. We used a regulated fluorescence affinity...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cd2536ef-3a14-5320-9b95-84526381c4e9
DOI: 10.1101/808709

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A lysophospholipase plays role in generation of neutral-lipids required for hemozoin formation in malaria parasiteDOI 10.1101/808709Read

<i>Plasmodium falciparum</i> diacylglycerol acyltransferase maintains phospholipid homeostasis to regulate sexual differentiation, ER stress, and cytoadhesionSemantic proximity Read

Pivotal roles of <i>Plasmodium falciparum</i> lysophospholipid acyltransferase 1 in cell cycle progression and cytostome internalizationSemantic proximity Read

Lipid Droplet, a Key Player in Host-Parasite InteractionsSemantic proximity Read

Lipid hijacking: A unifying theme in vector-borne diseasesSemantic proximity Read

Metabolism of host lysophosphatidylcholine in <i>Plasmodium falciparum</i> -infected erythrocytesSemantic proximity Read

A malaria parasite phospholipase facilitates efficient asexual blood stage egressSemantic proximity Read

Characterisation of Two <i>Plasmodium</i> Virulence Factors Important for Lipid Metabolism and Disease Progression <i>In Vivo</i>Semantic proximity Read

The flexibility of Apicomplexa parasites in lipid metabolismSemantic proximity Read

The acyl-CoA synthetase Tg ACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditionsSemantic proximity Read

Division and adaptation to host nutritional environment of apicomplexan parasites depend on apicoplast lipid metabolic plasticity and host organelles remodellingSemantic proximity Read

Activity-based protein profiling of human and plasmodium serine hydrolases and interrogation of potential antimalarial targetsSemantic proximity Read

Lipid metabolism in<i>Giardia</i>: a post-genomic perspectiveSemantic proximity Read