Article
Rab4 is an essential regulator of lysosomal trafficking in trypanosomes.
The Journal of biological chemistry - 22 Oct 2004
Hall Belinda S, Pal Arun, Goulding David, Field Mark C
Abstract excerpt
Rapid endocytosis and recycling of surface proteins are important processes common to most nucleated eukaryotic cells. The best characterized membrane recycling routes are mediated by the small GTPases Rab4 and Rab11, but the precise roles that these pathways play have not been fully elucidated. The protozoan Trypanosoma brucei has a highly developed endocytic system that is similar to that found in metazoans,...
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