Article
Promoter polymorphism of the 5-HT transporter and Alzheimer's disease.
Neuroscience letters - 10 Nov 2000
Hu M, Retz W, Baader M, Pesold B, Adler G, Henn F A, Rösler M, Thome J
Abstract excerpt
The role of the deletion/insertion polymorphism within the promoter region of the serotonin transporter gene (5-HTT) is under discussion as a potential genetic risk factor for Alzheimers's disease (AD). Here we report significant differences in the allelic distribution of this polymorphism with a higher frequency of the short variant allele in AD patients when compared to controls. This difference was independent...
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