Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cognitive impairment in studies of 5HTTLPR and psychosis in Alzheimer's disease: a systematic review.

Dementia and geriatric cognitive disorders - 1 Jan 2013

Creese Byron, Ballard Clive, Jones Emma

Abstract excerpt

BACKGROUND/AIMS: Cognitive impairment is a well-established correlate of psychotic symptoms in Alzheimer's disease (AD-P). We review whether this relationship has confounded previous genetic association studies of 5HTTLPR and AD-P. METHODS: We reviewed all studies on 5HTTLPR and conducted a semi-quantitative analysis. RESULTS: Three out of 4 studies with low MMSE reported a significant association, while 1 out of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Delusions
Share to Hallucinations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Psychiatric Status Rating Scales

Share to Psychotic Disorders

Share to Serotonin Plasma Membrane Transport Proteins

Share to Severity of Illness Index

Source

Identifiers

PMID: 23392273
DOI: 10.1159/000346733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cognitive impairment in studies of 5HTTLPR and psychosis in Alzheimer's disease: a systematic review.PMID 23392273Read ↗

Genetics of psychosis of Alzheimer disease.Semantic proximity Read ↗

Genome-wide association study of Alzheimer's disease with psychotic symptoms.Semantic proximity Read ↗

Psychotic symptoms in Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: evidence for an association.Semantic proximity Read ↗

Genetic and neurobiological aspects of psychosis in major neurocognitive disorder.Semantic proximity Read ↗

The Association between 5HT2A T102C and Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease: A Meta-Analysis.Semantic proximity Read ↗

Genetic risk for schizophrenia and psychosis in Alzheimer disease.Semantic proximity Read ↗

Genome-Wide Association Identifies the First Risk Loci for Psychosis in Alzheimer DiseaseSemantic proximity Read ↗

Serotonergic system genes in psychosis of Alzheimer dementia: meta-analysis.Semantic proximity Read ↗

Cumulative effect of COMT and 5-HTTLPR polymorphisms and their interaction with disease severity and comorbidities on the risk of psychosis in Alzheimer disease.Semantic proximity Read ↗

Association Between Psychosis Phenotype and APOE Genotype on the Clinical Profiles of Alzheimer's Disease.Semantic proximity Read ↗

Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease.Semantic proximity Read ↗

Association between schizophrenia polygenic score and psychotic symptoms in Alzheimer’s disease: meta-analysis of 11 cohort studiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.