Article
Sequence variants and functional analysis of human papillomavirus type 16 E5 gene in clinical specimens.
Archives of virology - 1 Jan 2000
Hsieh C H, Tsao Y P, Wang C H, Han C P, Chang J L, Lee J Y, Chen S L
Abstract excerpt
Previously, we found that the E5 protein can be expressed in HPV-16 infected precancerous lesions and cervical cancer. In this study, we investigated the presence of sequence variants of E5 in HPV-16 infected tissues. Toward this end, we amplified the E5 gene by polymerase chain reaction from 29 HPV-16 infected tissues including eight normal tissues, seven high grade neoplastic tissues (high grade squamous...
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