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Article

Sequence variation in the E2-binding domain of HPV16 and biological function evaluation in Tunisian cervical cancers.

BioMed research international - 1 Jan 2014

Kahla Saloua, Kochbati Lotfi, Hammami Samia, Chanoufi Mohamed Badis, Maalej Mongi, Oueslati Ridha

Abstract excerpt

HPV16 E2 variants have different effects on the transcriptional activity of the LCR. In this study, we examined the nucleotide and amino acid sequence variation within the HPV16 E2 gene and to correlate with disease progression. E2 gene disruption was detected by PCR amplification of the entire E2 gene using a single set of primers. Nucleotide variations were analyzed by bidirectional sequencing. mRNA expression...

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Source

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Identifiers

PMID: 25032221
DOI: 10.1155/2014/639321
PMCID: PMC4083599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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