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Human papillomavirus-16 E5 protein: oncogenic role and therapeutic value

19 Jan 2012

Abstract excerpt

BACKGROUND: Human papillomavirus (HPV) is a non-enveloped, double-stranded DNA virus. HPV infection occurs through sexual route, and the virus infects mucosal and cutaneous epithelial cells. Inside the cell, the viral DNA replicates extrachromosomally. HPV is the major cause of cervical cancer worldwide. HPVs infecting mucosal epithelial cells are sub-grouped into low-risk or high-risk by virtue of them causing...

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PMID: 22262402
DOI: 10.1007/s13402-011-0069-x

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