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Cellular Functions of HPV16 E5 Oncoprotein during Oncogenic Transformation

26 Oct 2020

Abstract excerpt

Abstract The human papillomavirus (HPV) is recognized as the main etiologic agent associated with cervical cancer. HPVs are epitheliotropic, and the ones that infect the mucous membranes are classified into low-risk (LR) and high-risk (HR) types. LR-HPVs produce benign lesions, whereas HR-HPVs produce lesions that may progress to cancer. HR-HPV types 16 and 18 are the most frequently found in cervical cancer...

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PMID: 33106372
DOI: 10.1158/1541-7786.mcr-20-0491

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