Article
Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle.
Journal of virology - 1 Mar 2003
Genther Sybil M, Sterling Stephanie, Duensing Stefan, Münger Karl, Sattler Carol, Lambert Paul F
Abstract excerpt
Human papillomaviruses (HPVs) are small circular DNA viruses that cause warts. Infection with high-risk anogenital HPVs, such as HPV type 16 (HPV16), is associated with human cancers, specifically cervical cancer. The life cycle of HPVs is intimately tied to the differentiation status of the host epithelium and has two distinct stages: the nonproductive stage and the productive stage. In the nonproductive stage,...
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