Article
Is interleukin-6 important in inflammatory bowel disease?
Genes and immunity - 1 Feb 2000
Koss K, Satsangi J, Welsh K I, Jewell D P
Abstract excerpt
The IL-6 gene maps to an area of chromosome 7 known to be significant for susceptibility to inflammatory bowel disease. The functional effects of interleukin-6 (IL-6) polymorphisms in the 4th intron and in the 3' flanking region of IL-6 gene were studied in 192 inflammatory bowel disease patients and healthy subjects. A polymerase chain reaction with sequence-specific primers (PCR-SSP) was used to determine a G...
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