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Article

Linkage of human tumor necrosis factor-alpha to human osteoporosis by sib pair analysis.

Genes and immunity - 1 Jan 2000

Ota N, Hunt S C, Nakajima T, Suzuki T, Hosoi T, Orimo H, Shirai Y, Emi M

Abstract excerpt

Osteoporosis as well as osteopenia are common human conditions considered to result from the interplay of multiple genetic and environmental factors. Twin and family studies have yielded strong correlation between measures of bone mass and a number of genetic factors. Certain genes (e.g., cytokines such as interleukin-1, interleukin-6, or tumor necrosis factor-alpha) are capable of regulating metabolism,...

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PMID: 11196702
DOI: 10.1038/sj.gene.6363668

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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