Article
Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis.
Human genetics - 1 Sept 1999
Ota N, Hunt S C, Nakajima T, Suzuki T, Hosoi T, Orimo H, Shirai Y, Emi M
Abstract excerpt
Osteopenia and osteoporosis are common human conditions considered to result from the interplay of multiple genetic and environmental factors. Twin and family studies have yielded strong correlations between levels of bone mass and a number of genetic factors. The genes involved could regulate metabolism, formation and resorption of bone, all processes that determine bone mass. We tested 192 sibling pairs of...
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