Article
[Prophylactic thyroidectomy in carriers of RET oncogene mutation carriers].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke - 10 Nov 2000
Høie J, Heimdal K, Nesland J M, Børmer O
Abstract excerpt
BACKGROUND: Medullary thyroid cancer may be inherited dominantly. Germline mutations in the RET oncogene which code for a receptor tyrosine kinase cause MEN2. Thyroidectomy is recommended in family members who carry a mutation. MATERIAL AND METHODS: We have thyroidectomized four children from three families, 12, 10, 7 and 6 years old, because of germline mutations. RESULTS: The 12-year-old had developed a minimal...
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