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Article

Role of prophylactic thyroidectomy in RET 790 familial medullary thyroid carcinoma.

Head & neck - 1 Apr 2012

Bihan Hélène, Baudin Eric, Meas Taly, Leboulleux Sophie, Al Ghuzlan Abir, Hannoteaux Véronique, Travagli Jean-Paul, Valleur Patrice, Guillausseau Pierre-Jean, Cohen Régis

Abstract excerpt

BACKGROUND: We describe a family harboring RET 790 mutation and review the role of prophylactic thyroidectomy for medullary thyroid carcinoma. METHODS: We evaluated in detail both clinical and biological follow-up and reviewed literature reports. RESULTS: Among 86 family members, 15 of 22 members screened harbored the 790 mutation. Abnormal calcitonin levels were found in 8/15. Total thyroidectomy with lymph node...

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Share to Carcinoma, Medullary
Share to Multiple Endocrine Neoplasia Type 2a

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplastic Syndromes, Hereditary

Share to Primary Prevention

Share to Proto-Oncogene Proteins c-ret

Share to Sampling Studies

Share to Thyroid Neoplasms

Share to Thyroidectomy

Source

Identifiers

PMID: 21688339
DOI: 10.1002/hed.21763

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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