Medullary thyroid carcinoma. Genetic screening and prophylactic thyroidectomies.

doi:10.2298/aci0303121b

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Article

Medullary thyroid carcinoma. Genetic screening and prophylactic thyroidectomies.

Acta chirurgica Iugoslavica - 1 Jan 2003

Bergant D, Hocevar M

Abstract excerpt

Medullary thyroid cancer is a rare, neuroendocrine, tumor. It arises from parafollicular or C-cells with the ability to produce and secrete different bioactive substances like calcitonin (TC) and CEA (1-5) TC is ideal tumor marker in early diagnosis, in patents' follow up and in evaluation of their treatment. TC determinations after ca/pentagastrine stimulation test give us even more accurate results and the...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Carcinoma, Medullary
Child
Female
Genetic Predisposition to Disease
Genetic Testing
Germ-Line Mutation
Humans
Male
Middle Aged
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-ret
Receptor Protein-Tyrosine Kinases
Thyroid Neoplasms
Thyroidectomy

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Open in PubMed

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PMID: 15179767
DOI: 10.2298/aci0303121b

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