Article
Is thyroidectomy necessary in RET mutations carriers of the familial medullary thyroid carcinoma syndrome?
Cancer - 15 Aug 2000
Hansen H S, Torring H, Godballe C, Jäger A C, Nielsen F C
Abstract excerpt
BACKGROUND: The results and consequences of genetic testing in a family with familial medullary thyroid carcinoma (FMTC) are described. METHODS: In the screening of relatives, serum calcitonin is replaced by RET mutation analysis that was performed in families suspected of hereditary medullary thyroid carcinoma (MTC). In 4 of 10 families, mutation in exon 10 was found in codon 611. RESULTS: One hundred fifty...
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