Article
[Early therapeutic management of patients genetically predisposed to medullary thyroid cancer].
Annales de chirurgie - 1 Jan 1998
Murat A, Modigliani E, Conte-Devolx B, Rohmer V, Leclerc L, Guilhem I, Bigorgne J C, Boneu A, Maes B, Chabre O, Niccoli P, Schuffenecker I, Giraud S
Abstract excerpt
STUDY: The aim of our study was to study therapeutic results after thyroidectomy in patients positive for predictive genetic analysis and with preoperative calcitonin (CT) response to pentagastlin (Pg) < 150 pg/ml. MATERIAL AND METHODS: 36 patients (13 F, 23 M) were selected: 13 F-MTC from 8 families, 22 MEN 2A from 15 families and 1 MEN 2B. They were positive for direct RET mutation analysis. CT was assayed by...
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