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Article

Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center.

Journal of the American College of Surgeons - 1 Aug 2002

Rodríguez González Jose M, Balsalobre María D, Pomares Francisco, Torregrosa Nuria M, Ríos Antonio, Carbonell Pablo, Glower Guillermo, Sola Joaquín, Tébar Javier, Parrilla Pascual

Abstract excerpt

BACKGROUND: Genetic study of the RET proto-oncogene has modified the management, treatment, and prognosis of medullary thyroid carcinoma (MTC), multiple endocrine neoplasia 2A (MEN 2A), for patients with less advanced tumor stages. Classically, the diagnosis was based on an increase in basal and poststimulus peak calcitonin (bCT and pCT). Prophylactic thyroidectomy, based on results of genetic testing, may reduce...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12168961
DOI: 10.1016/s1072-7515(02)01220-6

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center.PMID 12168961Read ↗

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Prophylactic thyroidectomies in MEN2 syndrome: Management and outcomes.Semantic proximity Read ↗

Molecular genetics and phenomics of RET mutations: Impact on prognosis of MTC.Semantic proximity Read ↗

[Prophylactic thyroidectomy in children and young people with hereditary medullary thyroid carcinoma: a Chilean experience].Semantic proximity Read ↗

The timing of total thyroidectomy in RET gene mutation carriers could be personalized and safely planned on the basis of serum calcitonin: 18 years experience at one single center.Semantic proximity Read ↗

Early, Prophylactic Thyroidectomy in Hereditary Medullary Thyroid Carcinoma: A 26-year Monoinstitutional Experience.Semantic proximity Read ↗

Update on the MEN 2A c804 RET mutation: is prophylactic thyroidectomy indicated?Semantic proximity Read ↗

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Prophylactic thyroidectomy in multiple endocrine neoplasia type 2A.Semantic proximity Read ↗

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