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Article

Novel dimerization fold of RAP30/RAP74 in human TFIIF at 1.7 A resolution.

Journal of molecular biology - 6 Oct 2000

Gaiser F, Tan S, Richmond T J

Abstract excerpt

General transcription factor IIF (TFIIF) is required for transcription by RNA polymerase II; it consists minimally of a heterodimer of RNA polymerase-associated proteins RAP30 and RAP74. According to solution and mutagenesis studies, the multiple domains of RAP30 and RAP74 bind PolII, TFIIB, TAF250 and DNA in interactions that are essential for transcription initiation and elongation. The X-ray structure of the...

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Identifiers

PMID: 11183778
DOI: 10.1006/jmbi.2000.4110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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