Article
Innate resistance to infection by intracellular bacterial pathogens differs in mice selected for maximal or minimal acute inflammatory response.
European journal of immunology - 1 Sept 1998
Araujo L M, Ribeiro O G, Siqueira M, De Franco M, Starobinas N, Massa S, Cabrera W H, Mouton D, Seman M, Ibañez O M
Abstract excerpt
The intensity of nonspecific immune reaction and the host resistance to facultative intracellular pathogens are found to be associated in lines of mice selected for maximal (AIRmax) or minimal (AIRmin) acute inflammatory reactivity. AIRmax are more resistant than AIRmin mice to Salmonella typhimurium and Listeria monocytogenes infection, the differences between lines in LD50 being > 1000 and 100 times,...
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