Article
Mutations in gyrA, gyrB, parC, and parE in quinolone-resistant strains of Neisseria gonorrhoeae.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Sept 2002
Lindbäck Emma, Rahman Motiur, Jalal Shah, Wretlind Bengt
Abstract excerpt
Mutations in the genes for the subunits GyrA and ParC of the target enzymes DNA gyrase and topoisomerase IV are important mechanisms of resistance in quinolone-resistant bacteria, including Neisseria gonorrhoeae. The target enzymes also consist of the subunits GyrB and ParE, respectively, though their role in quinolone-resistance has not been fully investigated. We sequenced the quinolone-resistance-determining...
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