Article
Plasmodium falciparum malaria in Laos: chloroquine treatment outcome and predictive value of molecular markers.
The Journal of infectious diseases - 1 Mar 2001
Pillai D R, Labbé A C, Vanisaveth V, Hongvangthong B, Pomphida S, Inkathone S, Zhong K, Kain K C
Abstract excerpt
A 28-day treatment trial was undertaken, to determine the efficacy of chloroquine in Laos and to assess the predictive value of molecular markers (cg2, pfmdr1, and pfcrt) that were previously linked to chloroquine resistance. In total, 522 febrile patients were screened for falciparum malaria by rapid diagnostic assays. Of 81 patients (15.5% prevalence) who were positive by the assays and microscopy, 48 were...
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